Advancements in extrusion-spheronisation

In recent years, pellets have gained considerable popularity as multi-particulate delivery systems owing to an array of benefits such as, more even and predictable distribution of the active pharmaceutical ingredient (API), the possibility of delivering multiple APIs in one dose, reduced potency and a lowered risk of side effects for the patient.

One of the most widely used methods of pelletisation is extrusion-spheronisation as it produces pellets with a high drug loading capacity, making it particularly effective when developing and manufacturing poorly soluble APIs.

Our R&D manager, Beata Vladovicova, PhD discusses the benefits of pelletisation and using extrusion-spheronisation to produce multi-particulate drugs with Pharmaceutical Technology. Read the full article here:

Download our full pelletisation whitepaper here:

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